Successful Pregnancy in Recurrent Thin Endometrium with New Uses for an Old Drug

Adequate growth of the endometrium is an important factor for successful implantation. Some authors have reported that there is a steady and gradual increase in pregnancy rates as endometrial thickness increases [1]. When endometrial thickness is <6 mm, the probability of achieving a full-term pregnancy decreases [2]. In order to maximize pregnancy rates, endometrial thickness from 8 mm to 14 mm was suggested [3]. There were 0.3% of patients in our center did not reach 6 mm as a thin endometrium [2]. In our center, endometrial thickness <6 mm is a criterion for fresh IVF cycle cancellation and all embryos will be cryopreserved with hoping for better endometrium growth in future Frozen Embryo Transfer (FET) cycles. However, improving endometrial growth in such patients is very difficult.